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Building the Future of Healthspan: Inside the Launch of the Longevity Biotech Fellowship

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In the quiet corridors of academic labs, in startup incubators, and at the heart of growing biotech hubs, a bold idea is taking root: that aging is not an inevitable decline, but a solvable biological puzzle. This vision, once fringe, is now entering the mainstream—thanks in part to a new wave of leaders who are […]

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The Power of Collective Vision: Reflecting on a Transformative Year for the Longevity Investor Network

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In the rapidly evolving world of healthspan and longevity, 2023 was a year defined not only by scientific discovery but by collaboration, capital, and community. The Longevity Investor Network (LIN), a mission-driven initiative connecting forward-thinking investors with transformative biotech and health companies, stood at the heart of that evolution. As the year drew to a

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Clearing the Cellular Clutter: Lewis Gruber and the Promise of Senotherapeutics

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Aging, as we now understand it, is not merely the passage of time—it’s a gradual accumulation of dysfunction. At the heart of this process lies a critical but often underappreciated player: the senescent cell. These cells, sometimes called “zombie cells,” were once healthy participants in our biology. But after reaching the end of their replicative

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How Cellular Reprogramming May Reshape Female Fertility: Insights from Yamanaka Factors in Rats

Cell & Gene Research / Leave a Comment

In the ever-evolving world of longevity science, few discoveries have generated as much excitement — and cautious hope — as cellular reprogramming. At the center of this revolution are the so-called Yamanaka factors: a set of four genes (OCT4, SOX2, KLF4, and c-MYC) that earned Shinya Yamanaka the Nobel Prize for their ability to reset

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Exosomes and Heart Health: A New Frontier in Regenerative Longevity Science

Cell & Gene Research / Leave a Comment

As longevity science moves beyond simply managing chronic disease and into restoring function at the cellular level, one emerging field stands out: exosome therapy. These microscopic messengers may soon reshape how we approach some of the most challenging aspects of aging — particularly when it comes to preserving and rejuvenating heart health. A growing body

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The Balancing Act of Aging: How Limiting One Cellular Pathway Unlocks Another

AI & Bioinformatics / Leave a Comment

Aging is more than a matter of years—it’s a matter of maintenance. Deep within our cells, a vast and intricate system works to maintain what scientists call proteostasis, or protein homeostasis: the ongoing process of creating, folding, managing, and discarding proteins. It’s an elegant choreography, one that keeps us functioning smoothly. But like any long-running

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Niacin and NAD+: A Simple Vitamin with Powerful Anti-Aging Potential

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A new human trial reveals how a humble nutrient could hold the key to cellular energy, metabolic resilience, and longer healthspan When we think of longevity-enhancing molecules, the mind often jumps to cutting-edge biotech or exotic compounds. But sometimes, the most powerful interventions come from simple, time-tested sources—like niacin, also known as vitamin B3. A

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Urolithin A: How a Gut Molecule May Calm the Flames of Aging

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The Silent Strain of Aging Aging is more than wrinkles or greying hair. At its core, aging is cellular: a slow, intricate unraveling of biological processes that can lead to dysfunction, inflammation, and disease. Among the most studied culprits in this decline is cellular senescence—a state where cells stop dividing but refuse to die. Like

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The Science of Heat: How Sauna Therapy Supports Longevity and Whole-Body Wellness

Human Health / Leave a Comment

Exploring the emerging research behind this ancient practice—and why modern science is rediscovering its remarkable benefits for aging well For thousands of years, cultures across the world have embraced the healing power of heat. From the Finnish sauna to Native American sweat lodges, humans have instinctively sought refuge in warm, enclosed spaces—not just for comfort,

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The Longevity Power of Food: How Dietary Choices Shape Healthy Aging

Human Health / Leave a Comment

You Are What You Eat — Especially As You Age As we navigate the shifting tides of aging, many of us seek to maintain not just longevity, but vitality—mental clarity, physical independence, emotional resilience. While exercise, genetics, and stress management all play roles, one powerful lever is within daily reach: the food we eat. A

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