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Some Stem Cells Remain Youthful With Age: What This Reveals About Aging, Resilience, and Longevity

A groundbreaking discovery highlights how certain stem cells preserve their youth — and what it may mean for extending healthspan Aging has long been associated with an inevitable decline — a slow unraveling of biological resilience, where cells lose their regenerative capacity, tissues wear out, and organs falter. But what if aging isn’t entirely universal? […]

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Plasma Exchange and Aging: A Human Trial Offers New Clues to Reversing the Biological Clock

In the race to unlock the secrets of healthy aging, some of the most promising breakthroughs are emerging not from exotic pharmaceuticals or futuristic gene therapies, but from an unexpected source: our own blood plasma. For years, scientists have speculated that the composition of blood — specifically, the proteins, signaling molecules, and circulating factors in

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Rejuvenating the Aging Brain: A Bold New Study Signals Hope for Cognitive Longevity

As the scientific quest to extend healthspan continues to accelerate, one of the most urgent frontiers lies within our own minds: how can we preserve cognitive vitality as we age? While many people fear physical frailty, even more dread the gradual erosion of memory, attention, and executive function that so often accompanies aging. The loss

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The Hidden Ally in Your Gut: How Urolithin A Helps Calm Inflammation and Rewire Aging

Aging Is Not Inevitable—At Least Not the Way We Once Thought We all age, but not all of us age in the same way. For decades, aging was seen as a slow, steady breakdown—an unavoidable decline in function. But that view is rapidly evolving. Today, science paints a more nuanced picture: aging is not just

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Rapamycin and Caloric Restriction: Distinct Paths to Longevity

Why rapamycin’s life-extending power does not depend on mimicking a calorie-restricted diet—and what this means for the future of age-defying science In the growing world of longevity research, two of the most studied and celebrated interventions are caloric restriction and rapamycin. Both have been shown to extend lifespan in laboratory animals and improve markers of

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Engineering Cellular Resilience: How Expressing a Mitochondrial Gene in the Nucleus May Help Us Age Better

A groundbreaking study in mice opens new doors in mitochondrial medicine—and offers clues for enhancing energy, resilience, and longevity at the cellular level Deep within every cell in your body, two genomes coexist. One resides in the nucleus, home to over 99% of your genetic material. The other—a tiny, powerful remnant of ancient bacteria—lives in

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The Lingering Shadow: How Even Mild COVID-19 Can Affect Brain Health

Understanding the Lasting Neurological Impact of a Pandemic Most Thought We Survived In the early days of the COVID-19 pandemic, attention was rightly focused on immediate respiratory complications, hospitalization rates, and saving lives. But now, years later, as we continue to recover socially and medically from the crisis, a quieter and more persistent challenge has

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Betting on a Longer, Healthier Future: Inside the Launch of LongGame, a Bold New Longevity Venture Fund

At the intersection of biotechnology and bold vision lies one of the most ambitious developments in longevity innovation this year: the official launch of LongGame, a venture capital fund dedicated entirely to extending human healthspan through cutting-edge science. Founded by crypto pioneer Will Harborne and built with a team of elite thinkers and operators from

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Dining with Bryan Johnson: A Glimpse Inside the Longevity Lifestyle Experiment

In the fast-evolving world of longevity science, few names provoke more curiosity, debate, and intrigue than Bryan Johnson. The tech entrepreneur-turned-biohacker has become a symbol of modern self-experimentation, drawing global attention with his radical lifestyle protocols aimed at reversing his biological age. But what does it actually feel like to step inside the world of

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Harnessing the Power of the Gut: How Urolithin A Helps Calm Aging at the Cellular Level

Aging is more than wrinkles and gray hair—it’s a slow, persistent change that begins deep within our cells. But what if we could gently influence how those changes unfold, not through drastic interventions but by working with the body’s own processes? Recent research suggests that a remarkable molecule derived from our gut microbiome—called Urolithin A—may

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