Drug Development

Urolithin A: The Gut-Derived Molecule Offering a New Path to Healthy Aging

A Quiet Revolution in Cellular Health What if the key to slowing aging wasn’t found in a high-tech laboratory or a far-off land, but rather in your gut—quietly produced by microbes each time you enjoy a handful of walnuts or a glass of pomegranate juice? Enter Urolithin A, a postbiotic compound emerging at the intersection […]

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The Gut-Brain-Aging Axis: How Urolithin A Quietly Supports Cellular Renewal and Longevity

Rethinking Aging at the Cellular Level Aging is often portrayed as a slow decline—an unavoidable cascade of wear and tear. But emerging science is challenging that idea. Increasingly, longevity research is revealing that aging is not simply a matter of time, but of biology—specifically, how well our cells manage damage, communicate, and repair themselves. One

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Clearing the Brain’s Clutter: Early Results from a Senolytic Trial for Alzheimer’s

How targeting cellular “zombies” offers a new approach to one of the world’s most devastating brain diseases Alzheimer’s disease remains one of the most heartbreaking frontiers in medicine. Despite decades of research, its progression remains stubbornly difficult to halt, and the toll on patients, families, and caregivers is immense. But behind the frustration lies a

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Urolithin A: The Gut’s Silent Ally in the Fight Against Inflammaging

Rethinking the Biology of Aging Aging is often perceived as an inevitable process, a slow unraveling of systems, and a steady march toward decline. But this view is rapidly being rewritten by advances in science. Researchers are increasingly seeing aging not as a passive accumulation of years but as a dynamic, biological phenomenon—one that can

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Spermidine: The Molecule That May Help Protect Cognitive Function Across Species

How this natural compound is showing promise for brain health and longevity in flies, mice, and humans For anyone invested in the science of healthy aging, cognitive resilience sits at the very heart of the conversation. Preserving memory, focus, and mental clarity as we age isn’t simply about adding more years to life — it’s

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The Small but Mighty Molecule Offering New Hope in Atherosclerosis

How cutting-edge research is unlocking the potential of a novel molecule to target the root causes of cardiovascular aging Few health threats cast a shadow as wide as atherosclerosis. This silent, progressive hardening and narrowing of the arteries remains one of the world’s leading causes of death, responsible for heart attacks, strokes, and vascular dementia.

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Energizing Aging Muscles: How NMN May Improve Glucose Metabolism and Insulin Sensitivity

A human clinical trial reveals new benefits of this NAD+ precursor, offering fresh hope for metabolic health and age-related energy decline As we age, it’s not uncommon to feel our muscles slow down. Whether it’s longer recovery times, more fatigue during workouts, or subtle dips in strength and mobility, these changes often trace back to

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Old Drugs, New Hope: Exploring the Potential of Repurposed Medications to Lower Dementia Risk

How familiar pharmaceuticals may offer surprising benefits in the fight against cognitive decline In the world of medicine, few challenges are as formidable—or as emotionally charged—as dementia. With its slow erosion of memory, personality, and independence, dementia touches not just the individual but entire families. It remains one of the most feared consequences of aging.

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Rebalancing the Aging Immune System: A Three-Part Nutritional Strategy for Inflammaging

Aging is inevitable, but the way we age is anything but fixed. Beneath the surface of visible wrinkles and gray hair, our immune systems gradually shift into a state of imbalance — a persistent, low-grade inflammation that quietly undermines health over decades. This process, known as inflammaging, is increasingly recognized as a foundational driver of

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The Next Evolution in NAD+ Support: What You Should Know About Reduced Nicotinamide Mononucleotide (NMNH)

A groundbreaking discovery introduces a powerful new molecule for cellular health and longevity—and it might be even more effective than NMN In the search for ways to live longer and age better, few molecules have attracted as much attention as NAD+ (nicotinamide adenine dinucleotide). It’s not just a scientific buzzword—it’s a central player in energy

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